منابع مشابه
Mitigating the dangers of opioids.
JAMA InternalMedicinehas run a series of articles on thedangersofprescriptionopioids for the treatmentof chronicpain.1,2 Thebest solution is toavoidprescribingopioids forchronicpain because there is no high-quality evidence that they are effective for this indication, and the risk of adverse effects, including death from unintentional overdose, is great.3 But whenpatientsare inpain, andnonopioi...
متن کاملMitigating Harm: Considering Harm Reduction Principles in Work with Sexually Exploited Young People
A growing awareness of child sexual exploitation (CSE) in the United Kingdom and throughout the world has prompted human service and legal/policy professionals to seek ways of engaging young people experiencing sexual exploitation, although much remains unknown regarding effective practice, and whether or not current knowledge regarding best practices with young people can be expanded to addres...
متن کاملPolypharmacy and chronic pain: harm exposure is not all about the opioids.
OBJECTIVE AND DESIGN Individuals seeking treatment for chronic pain in multidisciplinary pain management services are typically already on high doses of pain medications. This cross-sectional cohort study of patients with long-term chronic pain examined profiles of polypharmacy and pain medication-related harm exposure. SETTING Multidisciplinary pain management service. SUBJECTS The cohort ...
متن کاملاپوئیدها(Opioids) و دستگاه گوارش
SUMMARY The term opioid was coined to refer in a generic sense to all drugs, natural and synthetic, with morphin - like actions. Three distinct families of peptides have been identified so far in gastrointestinal (GI) nervous system in mammalian. These peptides include : dynorphin, Met - enkephalin and leu - enkephalin . Results from studies about opioid which have been started 15 years ago ...
متن کاملScale-up of a comprehensive harm reduction programme for people injecting opioids: lessons from north-eastern India.
PROBLEM Harm reduction packages for people who inject illicit drugs, including those infected with human immunodeficiency virus (HIV), are cost-effective but have not been scaled up globally. In the north-eastern Indian states of Manipur and Nagaland, the epidemic of HIV infection is driven by the injection of illicit drugs, especially opioids. These states needed to scale up harm reduction pro...
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ژورنال
عنوان ژورنال: Nature
سال: 2019
ISSN: 0028-0836,1476-4687
DOI: 10.1038/d41586-019-02689-z